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Article

Insights of fibroblast growth factor receptor 3 aberrations in pan-cancer and their roles in potential clinical treatment.

Aging - 23 Jun 2021

Li Juanni, Hu Kuan, Huang Jinzhou, Zhou Lei, Yan Yuanliang, Xu Zhijie

Abstract excerpt

Fibroblast growth factor receptor 3 (FGFR3) alters frequently across various cancer types and is a common therapeutic target in bladder urothelial carcinoma (BLCA) with FGFR3 variants. Although emerging evidence supports the role of FGFR3 in individual cancer types, no pan-cancer analysis is available. In this work, we used the open comprehensive datasets, covering a total of 10,953 patients with 10,967 samples...

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Identifiers

PMID: 34160364
DOI: 10.18632/aging.203175
PMCID: PMC8266346

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