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Article

A Phenotypic Screen for Functional Mutants of Human Adenosine Deaminase Acting on RNA 1.

ACS chemical biology - 20 Nov 2015

Wang Yuru, Havel Jocelyn, Beal Peter A

Abstract excerpt

Adenosine deaminases acting on RNA (ADARs) are RNA-editing enzymes responsible for the conversion of adenosine to inosine at specific locations in cellular RNAs. ADAR1 and ADAR2 are two members of the family that have been shown to be catalytically active. Earlier, we reported a phenotypic screen for the study of human ADAR2 using budding yeast S. cerevisiae as the host system. While this screen has been...

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Identifiers

PMID: 26372505
DOI: 10.1021/acschembio.5b00711
PMCID: PMC4900682

Genes

ADAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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