Article
β2-Adrenergic receptor promoter haplotype influences the severity of acute viral respiratory tract infection during infancy: a prospective cohort study.
BMC medical genetics - 14 Sept 2015
Wu Pingsheng, Larkin Emma K, Reiss Sara S, Carroll Kecia N, Summar Marshall L, Minton Patricia A, Woodward Kimberly B, Liu Zhouwen, Islam Jessica Y, Hartert Tina V, Moore Paul E
Abstract excerpt
BACKGROUND: Despite the significant interest in β2-Adrenergic receptor (ADRB2) polymorphisms related to asthma, whether ADRB2 genetic variants are similarly associated with acute respiratory tract infections have not been studied. We hypothesized that genetic variants in ADRB2 associated with a response to asthma therapy during an asthma exacerbation were also associated with severity of acute respiratory tract...
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