Article
Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program.
The Journal of allergy and clinical immunology - 1 Nov 2003
Silverman Edwin K, Kwiatkowski David J, Sylvia Jody S, Lazarus Ross, Drazen Jeffrey M, Lange Christoph, Laird Nan M, Weiss Scott T
Abstract excerpt
BACKGROUND: Beta2-adrenergic receptor (B2AR) polymorphisms have been associated with a variety of asthma-related phenotypes, but association results have been inconsistent across different studies. OBJECTIVE: We sought to apply family-based association methods to individual single nucleotide polymorphisms (SNPs) and haplotypes of SNPs in B2AR to define the relationship of these genetic variants to asthma-related...
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