Article
Elimination of metabolic pathways to all traditional fermentation products increases ethanol yields in Clostridium thermocellum.
Metabolic engineering - 1 Nov 2015
Papanek Beth, Biswas Ranjita, Rydzak Thomas, Guss Adam M
Abstract excerpt
Clostridium thermocellum has the natural ability to convert cellulose to ethanol, making it a promising candidate for consolidated bioprocessing (CBP) of cellulosic biomass to biofuels. To further improve its CBP capabilities, a mutant strain of C. thermocellum was constructed (strain AG553; C. thermocellum Δhpt ΔhydG Δldh Δpfl Δpta-ack) to increase flux to ethanol by removing side product formation. Strain AG553...
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