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Article

Mutant selection and phenotypic and genetic characterization of ethanol-tolerant strains of Clostridium thermocellum.

Applied microbiology and biotechnology - 1 Nov 2011

Shao Xiongjun, Raman Babu, Zhu Mingjun, Mielenz Jonathan R, Brown Steven D, Guss Adam M, Lynd Lee R

Abstract excerpt

Clostridium thermocellum is a model microorganism for converting cellulosic biomass into fuels and chemicals via consolidated bioprocessing. One of the challenges for industrial application of this organism is its low ethanol tolerance, typically 1-2% (w/v) in wild-type strains. In this study, we report the development and characterization of mutant C. thermocellum strains that can grow in the presence of high...

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PMID: 21874277
DOI: 10.1007/s00253-011-3492-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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