Article
Prognostic significance of PLA2G4C gene polymorphism in patients with stage II colorectal cancer.
Acta oncologica (Stockholm, Sweden) - 1 Jan 2016
Olsen Renate S, Andersson Roland E, Zar Niklas, Löfgren Sture, Wågsäter Dick, Matussek Andreas, Dimberg Jan
Abstract excerpt
BACKGROUND: Phospholipase A2 Group IV C (PLA2G4C) catalyzes the release of certain fatty acids from phospholipids and plays a role in a range of physiological functions, such as remodeling of cell membranes and the production of prostaglandins. Furthermore, it has been proposed that PLA2G4C plays an important role in breast cancer cell chemotaxis. This study aimed to investigate the effect of a single nucleotide...
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