Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The -765C allele of the cyclooxygenase-2 gene as a potential risk factor of colorectal cancer: a meta-analysis.

The Tohoku journal of experimental medicine - 1 Sept 2010

Cao Hui, Xu Zhong, Long Hao, Li Xiao-qing, Li Shao-lin

Abstract excerpt

Colorectal cancer (CRC) is the third leading cause of cancer-related death in the world. Human colorectal carcinogenesis is a complex, multistep and multigenetic process. Cyclooxygenase-2 (COX2), a key enzyme in arachidonic acid metabolism, is overexpressed in several epithelial malignancies including colorectal cancer. COX2 expression can be induced by pro-inflammatory and mitogenic stimuli. The -765G/C...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Colorectal Neoplasms
Share to Cyclooxygenase 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 20808059
DOI: 10.1620/tjem.222.15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The -765C allele of the cyclooxygenase-2 gene as a potential risk factor of colorectal cancer: a meta-analysis.PMID 20808059Read ↗

Meta-analysis of the association between COX-2 polymorphisms and risk of colorectal cancer based on case-control studies.Semantic proximity Read ↗

COX-2 gene rs689466 polymorphism is associated with increased risk of colorectal cancer among Caucasians: a meta-analysis.Semantic proximity Read ↗

COX-2 gene rs689466 polymorphism is associated with increased risk of colorectal cancer among Caucasians: a meta-analysisSemantic proximity Read ↗

Cyclooxygenase-2 polymorphisms and susceptibility to colorectal cancer: a meta-analysis.Semantic proximity Read ↗

[Cyclooxygenase-2 -765G>C polymorphism and susceptibility to colorectal cancer: a meta-analysis].Semantic proximity Read ↗

The 765G>C polymorphism in the cyclooxygenase-2 gene and gastric cancer risk: an update by meta-analysis.Semantic proximity Read ↗

COX-2-765G>C polymorphism increases the risk of cancer: a meta-analysis.Semantic proximity Read ↗

The -765G>C polymorphism in the cyclooxygenase-2 gene and digestive system cancer: a meta-analysis.Semantic proximity Read ↗

Cyclooxygenase 2 polymorphism and colorectal cancer: -765G>C variant modifies risk associated with smoking and body mass index.Semantic proximity Read ↗

POLYMORPHISM OF THE COX-2 GENE AND SUSCEPTIBILITY TO COLON AND RECTAL CANCER.Semantic proximity Read ↗

PTGS2 (COX2) -765G>C gene polymorphism and risk of sporadic colorectal cancer in Iranian population.Semantic proximity Read ↗

-765G>C and 8473T>C polymorphisms of COX-2 and cancer risk: a meta-analysis based on 33 case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.