Article
Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk.
Carcinogenesis - 1 Mar 2010
Hoeft Birgit, Linseisen Jakob, Beckmann Lars, Müller-Decker Karin, Canzian Federico, Hüsing Anika, Kaaks Rudolf, Vogel Ulla, Jakobsen Marianne U, Overvad Kim, Hansen Rikke D, Knüppel Sven, Boeing Heiner, Trichopoulou Antonia, Koumantaki Yvoni, Trichopoulos Dimitrios, Berrino Franco, Palli Domenico, Panico Salvatore, Tumino Rosario, Bueno-de-Mesquita H B, van Duijnhoven Fränzel J B, van Gils Carla H, Peeters Petra H, Dumeaux Vanessa, Lund Eiliv, Huerta Castaño José M, Muñoz Xavier, Rodriguez Laudina, Barricarte Aurelio, Manjer Jonas, Jirström Karin, Van Guelpen Bethany, Hallmans Göran, Spencer Elizabeth A, Crowe Francesca L, Khaw Kay-Tee, Wareham Nick, Morois Sophie, Boutron-Ruault Marie-Christine, Clavel-Chapelon Françoise, Chajes Veronique, Jenab Mazda, Boffetta Paolo, Vineis Paolo, Mouw Traci, Norat Teresa, Riboli Elio, Nieters Alexandra
Abstract excerpt
Colorectal cancer (CRC) is the third most common malignant tumor and the fourth leading cause of cancer death worldwide. The crucial role of fatty acids for a number of important biological processes suggests a more in-depth analysis of inter-individual differences in fatty acid metabolizing genes as contributing factor to colon carcinogenesis. We examined the association between genetic variability in 43 fatty...
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