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Article

Impact of group IVA cytosolic phospholipase A2 gene polymorphisms on phenotypic features of patients with familial adenomatous polyposis.

International journal of colorectal disease - 1 Mar 2010

Umeno Junji, Matsumoto Takayuki, Esaki Motohiro, Kukita Yoji, Tahira Tomoko, Yanaru-Fujisawa Ritsuko, Nakamura Shotaro, Arima Hisatomi, Hirahashi Minako, Hayashi Kenshi, Iida Mitsuo

Abstract excerpt

OBJECTIVE: Group IVA cytosolic phospholipase A(2) (cPLA(2)alpha) plays a key role in tumorigenesis via generating arachidonic acids as the substrate of cyclooxygenase. The aim of this study was to elucidate the possible associations between cPLA ( 2 )alpha gene polymorphisms and phenotypic featur...

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Identifiers

PMID: 19795129
DOI: 10.1007/s00384-009-0808-x

Genes

FAP
APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19795129-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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