Article

Association of TNFα -308G/A and IL10 -1082A/G Polymorphisms with Pulmonary Tuberculosis Susceptibility in a Brazilian population

2022-11-19

Abstract excerpt

Pulmonary tuberculosis (PTB) remains a major cause of morbidity and mortality in developing countries. The course of Mycobacterium tuberculosis infection is regulated by mainly two antagonistic cytokines that are produced and secreted by T cells, TNF-α and IL-10. Differences in TNFα and IL10 genes expression and protein production affected by single nucleotide polymorphisms (SNPs) have been demonstrated influence...

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Literature Corpus work: af985bb1-21ad-5e0a-b8fc-fe46e7c5ced2
DOI: 10.21203/rs.3.rs-2150864/v1

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