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Article

Association of Cytokine Gene Polymorphisms and Their Impact on Active and Latent Tuberculosis in Brazil's Amazon Region.

Biomolecules - 18 Oct 2023

da Silva Graça Amoras Ednelza, de Morais Thais Gouvea, do Nascimento Ferreira Rafaella, Gomes Samara Tatielle Monteiro, de Sousa Francisca Dayse Martins, de Paula Souza Iury, Ishak Ricardo, Vallinoto Antonio Carlos Rosário, Queiroz Maria Alice Freitas

Abstract excerpt

Some genetic variations in cytokine genes can alter their expression and influence the evolution of Mycobacterium tuberculosis (Mtb) infection. This study aimed to investigate the association of polymorphisms in cytokine genes and variability in plasma levels of cytokines with the development of tuberculosis (TB) and latent tuberculosis infection (LTBI). Blood samples from 245 patients with TB, 80 with LTBI, and...

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Identifiers

PMID: 37892223
DOI: 10.3390/biom13101541
PMCID: PMC10605732

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