Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low levels of TNFA gene expression seem to favor the development of pulmonary tuberculosis in a population from the Brazilian Amazon.

Immunobiology - 1 Mar 2023

Sousa Francisca Dayse Martins de, Souza Iury de Paula, Amoras Ednelza da Silva Graça, Lima Sandra Souza, Cayres-Vallinoto Izaura Maria Vieira, Ishak Ricardo, Vallinoto Antonio Carlos Rosário, Queiroz Maria Alice Freitas

Abstract excerpt

TNF-α is a Th1 cytokine profile active in the control of Mycobacterium tuberculosis infection, IL-10 is associated with persistence of bacterial infection. The aim of the study was to investigate the association of TNFA -308G/A and IL10 -819C/T polymorphisms and TNFA and IL10 gene expression levels with pulmonary and extrapulmonary tuberculosis (n = 200) and control (n = 200). The individuals were submitted to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Interleukin-10

Share to Polymorphism, Single Nucleotide

Share to Tuberculosis, Pulmonary

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 36630812
DOI: 10.1016/j.imbio.2023.152333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low levels of TNFA gene expression seem to favor the development of pulmonary tuberculosis in a population from the Brazilian Amazon.PMID 36630812Read ↗

Association of TNFα -308G/A and IL10 -1082A/G Polymorphisms with Pulmonary Tuberculosis Susceptibility in a Brazilian populationSemantic proximity Read ↗

Genetic Polymorphism of Tumor Necrosis Factor-Alpha, Interferon-Gamma and Interleukin-10 and Association With Risk of Mycobacterium Tuberculosis Infection.Semantic proximity Read ↗

Association of TNF-α and IL-10 polymorphisms with tuberculosis in Tunisian populations.Semantic proximity Read ↗

Interleukin-10 and tumor necrosis factor-alpha gene polymorphisms in tuberculosis.Semantic proximity Read ↗

Toll-like receptors, tumor necrosis factor-α, and interleukin-10 gene polymorphisms in risk of pulmonary tuberculosis and disease severity.Semantic proximity Read ↗

Evaluation of TNF-α, IL-10 and IL-6 Cytokine Production and Their Correlation with Genotype Variants amongst Tuberculosis Patients and Their Household Contacts.Semantic proximity Read ↗

Association of TNF-α, IL-10 and IL-6 promoter polymorphisms in pulmonary tuberculosis patients and their household contacts of younger age group.Semantic proximity Read ↗

Genetic Polymorphisms in the Toll-like Receptor 10, Interleukin (IL)17A and IL17F Genes Differently Affect the Risk for Tuberculosis in Croatian Population.Semantic proximity Read ↗

Influence of TNF and IL10 gene polymorphisms in the immunopathogenesis of leprosy in the south of Brazil.Semantic proximity Read ↗

Genetic polymorphisms in TNF genes and tuberculosis in North Indians.Semantic proximity Read ↗

Association of Cytokine Gene Polymorphisms and Their Impact on Active and Latent Tuberculosis in Brazil's Amazon Region.Semantic proximity Read ↗

Effects of SNPs on TNF-α and IL-10 cytokine expression in TB and HIV patients in the Capricorn district, Limpopo Province, South Africa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.