Article

Hyperpolarization-activated cation channels shape the spiking frequency preference of human cortical layer 5 pyramidal neurons

2023-02-14

Abstract excerpt

Discerning the contribution of specific ionic currents to complex neuronal dynamics is a difficult, but important, task. This challenge is exacerbated in the human setting, although the widely-characterized uniqueness of the human brain as compared to preclinical models necessitates the direct study of human neurons. Neuronal spiking frequency preference is of particular interest given its role in rhythm generatio...

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Literature Corpus work: 1564b6cc-c8ed-5c73-b36d-9ed8285c9adb
DOI: 10.1101/2023.02.13.528352

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