Article

A maturation-associated ERG3/KCNH7 conductance tunes neural state-space stability and temporal-context prediction

2024-09-25

Abstract excerpt

<h4>SUMMARY</h4> Neural maturation must preserve flexible state dynamics while preventing those dynamics from becoming unstable, unreadable, or mismatched to learning. Here, I identify KCNH7, encoding the ERG3/Kv11.3 potassium channel, as a maturation-associated candidate regulator of such operating regimes. Public developmental, single-cell, and Patch-seq analyses linked KCNH7/ERG3 to late postnatal expression a...

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Literature Corpus work: 199a2de6-dd86-571f-8a4c-11759529a18b
DOI: 10.1101/2024.09.22.614315

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