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Article

Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin.

Scientific reports - 11 Sept 2015

Goh Justin B, Wallace Daniel F, Hong Wanjin, Subramaniam V Nathan

Abstract excerpt

BMP-SMAD signalling plays a crucial role in numerous biological processes including embryonic development and iron homeostasis. Dysregulation of the iron-regulatory hormone hepcidin is associated with many clinical iron-related disorders. We hypothesised that molecules which mediate BMP-SMAD signalling play important roles in the regulation of iron homeostasis and variants in these proteins may be potential...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26358513
DOI: 10.1038/srep13986
PMCID: PMC4566084

Genes

SMAD7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Endofin, a novel BMP-SMAD regulator of the iron-regulatory hormone, hepcidin.PMID 26358513Read ↗

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