Article
Bone morphogenetic proteins as regulators of iron metabolism.
Annual review of nutrition - 1 Jan 2014
Parrow Nermi L, Fleming Robert E
Abstract excerpt
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-beta (TGF-β) superfamily of signaling molecules. In addition to protean roles in embryonic development, germ-line specification, and cellular differentiation, a central role in iron homeostasis has recently been demonstrated for certain BMPs. Specifically, BMP6 serves to relate hepatic iron stores to the hepatocellular expression of...
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