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Article

ETV/Pea3 family transcription factor-encoding genes are overexpressed in CIC-mutant oligodendrogliomas.

Genes, chromosomes & cancer - 1 Dec 2015

Padul Vijay, Epari Sridhar, Moiyadi Aliasgar, Shetty Prakash, Shirsat Neelam Vishwanath

Abstract excerpt

Oligodendrogliomas with combined loss of chromosome arms 1p and 19q are known to be particularly sensitive to chemotherapy, and the CIC gene located on 19q is known to be mutated in over 50% of the 1p/19q codeleted oligodendrogliomas. However, the role of CIC in the oligodendroglioma pathogenesis is not known. Exome sequencing of 11 oligodendroglial tumors identified 9 tumors with combined loss of 1p and 19q....

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Source

Identifiers

PMID: 26357005
DOI: 10.1002/gcc.22283

Genes

CIC
KRAS
MAML3
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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