Article
CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas.
Acta neuropathologica - 1 Jun 2012
Sahm Felix, Koelsche Christian, Meyer Jochen, Pusch Stefan, Lindenberg Kerstin, Mueller Wolf, Herold-Mende Christel, von Deimling Andreas, Hartmann Christian
Abstract excerpt
CIC and FUBP1 mutations have recently been detected in oligodendrogliomas but not in oligoastrocytomas. However, allelic losses in the regions on chromosomal arms 19q and 1p harboring CIC and FUBP1 are a common feature of both, oligodendrogliomas and oligoastrocytomas. To resolve this discrepancy, we analyzed CIC and FUBP1 mutations in a set of primary brain tumors including 18 oligodendrogliomas and 42...
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