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Article

WDR5 Expression Is Prognostic of Breast Cancer Outcome.

PloS one - 1 Jan 2015

Dai Xiaofeng, Guo Wenwen, Zhan Chunjun, Liu Xiuxia, Bai Zhonghu, Yang Yankun

Abstract excerpt

WDR5 is a core component of the human mixed lineage leukemia-2 complex, which plays central roles in ER positive tumour cells and is a major driver of androgen-dependent prostate cancer cell proliferation. Given the similarities between breast and prostate cancers, we explore the potential prognostic value of WDR5 gene expression on breast cancer survival. Our findings reveal that WDR5 over-expression is...

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Identifiers

PMID: 26355959
DOI: 10.1371/journal.pone.0124964
PMCID: PMC4565643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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