Article

WDR5 regulates epithelial-to-mesenchymal transition in breast cancer cells <i>via</i> TGFβ

2018-06-16

Abstract excerpt

Even if the mortality rate in breast cancer (BC) has recently decreased, development of metastases and drug resistance are still challenges to successful systemic treatment. The epithelial-to-mesenchymal transition (EMT), as well as epigenetic dynamic modifications, plays a pivotal role in invasion, metastasis, and drug resistance. Here, we report that WDR5, the core subunit of histone H3 K4 methyltransferase comp...

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Literature Corpus work: bc21a200-1899-55cc-8f3f-a33c1495769b
DOI: 10.1101/348532

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