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Article

Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy.

Nature - 10 Sept 2015

Jaunmuktane Zane, Mead Simon, Ellis Matthew, Wadsworth Jonathan D F, Nicoll Andrew J, Kenny Joanna, Launchbury Francesca, Linehan Jacqueline, Richard-Loendt Angela, Walker A Sarah, Rudge Peter, Collinge John, Brandner Sebastian

Abstract excerpt

More than two hundred individuals developed Creutzfeldt-Jakob disease (CJD) worldwide as a result of treatment, typically in childhood, with human cadaveric pituitary-derived growth hormone contaminated with prions. Although such treatment ceased in 1985, iatrogenic CJD (iCJD) continues to emerge because of the prolonged incubation periods seen in human prion infections. Unexpectedly, in an autopsy study of eight...

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Identifiers

PMID: 26354483
DOI: 10.1038/nature15369

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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