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Article

Prion-like aggregates: infectious agents in human disease.

Trends in molecular medicine - 1 Nov 2010

Westermark Gunilla T, Westermark Per

Abstract excerpt

According to the 'protein only hypothesis', Creutzfeldt-Jakob disease and other prion disorders are transmissible by misfolded and aggregated prion proteins that act as templates for the misfolding of the same protein in the recipient. The misfolding and aggregation of the prion protein are akin to the genesis of amyloid fibrils formed by several human and animal proteins associated with more common diseases. Two...

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Identifiers

PMID: 20870462
DOI: 10.1016/j.molmed.2010.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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