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Article

Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease.

Lancet (London, England) - 15 Jun 1991

Collinge J, Palmer M S, Dryden A J

Abstract excerpt

The spongiform encephalopathy Creutzfeldt-Jakob disease (CJD) has been transmitted to man via administration of growth hormone and gonadotropin extracted from large pooled batches of human cadaveric pituitary glands. In the UK, 1908 individuals were exposed to potentially contaminated growth hormone, of whom 6 have so far manifested CJD. Examination of the prion protein genes of all these cases and of a single...

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PMID: 1675319
DOI: 10.1016/0140-6736(91)93128-v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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