Article
Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease.
Lancet (London, England) - 15 Jun 1991
Collinge J, Palmer M S, Dryden A J
Abstract excerpt
The spongiform encephalopathy Creutzfeldt-Jakob disease (CJD) has been transmitted to man via administration of growth hormone and gonadotropin extracted from large pooled batches of human cadaveric pituitary glands. In the UK, 1908 individuals were exposed to potentially contaminated growth horm...
Topics
- Alleles
- Creutzfeldt-Jakob Syndrome
- DNA
- Disease Susceptibility
- Gonadotropins, Pituitary
- Growth Hormone
- Homozygote
- Humans
- Iatrogenic Disease
- Polymerase Chain Reaction
- PrPSc Proteins
- Valine
- Viral Proteins