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Article

Prognostic role of PIK3CA mutations of cell-free DNA in early-stage triple negative breast cancer.

Cancer science - 1 Nov 2015

Takeshita Takashi, Yamamoto Yutaka, Yamamoto-Ibusuki Mutsuko, Inao Toko, Sueta Aiko, Fujiwara Saori, Omoto Yoko, Iwase Hirotaka

Abstract excerpt

PIK3CA is an oncogene that encodes the p110α component of phosphatidylinositol 3-kinase (PI3K); it is the second most frequently mutated gene following the TP53 gene. In the clinical setting, PIK3CA mutations may have favorable prognostic value for hormone receptor-positive breast cancer patients and, during the past few years, PIK3CA mutations of cell-free DNA (cfDNA) have attracted attention as a potential...

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Identifiers

PMID: 26353837
DOI: 10.1111/cas.12813
PMCID: PMC4714688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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