Article
Cell-free DNA as a molecular tool for monitoring disease progression and response to therapy in breast cancer patients.
Breast cancer research and treatment - 1 Jan 2016
Liang Diana H, Ensor Joe E, Liu Zhe-Bin, Patel Asmita, Patel Tejal A, Chang Jenny C, Rodriguez Angel A
Abstract excerpt
Due to the spatial and temporal genomic heterogeneity of breast cancer, genomic sequencing obtained from a single biopsy may not capture the complete genomic profile of tumors. Thus, we propose that cell-free DNA (cfDNA) in plasma may be an alternate source of genomic information to provide comprehensive data throughout a patient's clinical course. We performed a retrospective chart review of 100 patients with...
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