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Article

Dissection of PIK3CA Aberration for Cervical Adenocarcinoma Outcomes

28 Jun 2021

Abstract excerpt

Personalized treatment of genetically stratified subgroups has the potential to improve outcomes in many malignant tumors. This study distills clinically meaningful prognostic/predictive genomic marker for cervical adenocarcinoma using signature genomic aberrations and single-point nonsynonymous mutation-specific droplet digital PCR (ddPCR). Mutations in PIK3CA E542K, E545K, or H1047R were detected in 41.7% of...

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Cancer Genomics and Diagnostics
Cervical Cancer and HPV Research
Lung Cancer Treatments and Mutations

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34203201
DOI: 10.3390/cancers13133218

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