Detection of cancer DNA in plasma of patients with early-stage breast cancer.

doi:10.1158/1078-0432.CCR-13-2933

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Article

Detection of cancer DNA in plasma of patients with early-stage breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 May 2014

Beaver Julia A, Jelovac Danijela, Balukrishna Sasidharan, Cochran Rory, Croessmann Sarah, Zabransky Daniel J, Wong Hong Yuen, Toro Patricia Valda, Cidado Justin, Blair Brian G, Chu David, Burns Timothy, Higgins Michaela J, Stearns Vered, Jacobs Lisa, Habibi Mehran, Lange Julie, Hurley Paula J, Lauring Josh, VanDenBerg Dustin, Kessler Jill, Jeter Stacie, Samuels Michael L, Maar Dianna, Cope Leslie, Cimino-Mathews Ashley, Argani Pedram, Wolff Antonio C, Park Ben H

Abstract excerpt

PURPOSE: Detecting circulating plasma tumor DNA (ptDNA) in patients with early-stage cancer has the potential to change how oncologists recommend systemic therapies for solid tumors after surgery. Droplet digital polymerase chain reaction (ddPCR) is a novel sensitive and specific platform for mutation detection. EXPERIMENTAL DESIGN: In this prospective study, primary breast tumors and matched pre- and postsurgery...

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Identifiers

PMID: 24504125
DOI: 10.1158/1078-0432.CCR-13-2933
PMCID: PMC4024333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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