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Article

Diagnostic Accuracy of PIK3CA Mutation Detection by Circulating Free DNA in Breast Cancer: A Meta-Analysis of Diagnostic Test Accuracy.

PloS one - 1 Jan 2016

Zhou Yidong, Wang Changjun, Zhu Hanjiang, Lin Yan, Pan Bo, Zhang Xiaohui, Huang Xin, Xu Qianqian, Xu Yali, Sun Qiang

Abstract excerpt

Mutation of p110 alpha-catalytic subunit of phosphatidylinositol 3-kinase (PIK3CA) has high predictive and prognostic values for breast cancer. Hence, there has been a marked interest in detecting and monitoring PIK3CA genotype with non-invasive technique, such as circulating free DNA (cfDNA). However, the diagnostic accuracy of PIK3CA genotyping by cfDNA is still a problem of controversy. Here, we conducted the...

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Identifiers

PMID: 27336598
DOI: 10.1371/journal.pone.0158143
PMCID: PMC4918940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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