Article
An interaction between NDE1 and high birth weight increases schizophrenia susceptibility.
Psychiatry research - 15 Dec 2015
Wegelius Asko, Pankakoski Maiju, Tomppo Liisa, Lehto Ulriika, Lönnqvist Jouko, Suvisaari Jaana, Paunio Tiina, Hennah William
Abstract excerpt
Pre- and perinatal environmental factors have been shown to increase schizophrenia risk particularly when combined with genetic liability. The investigation of specific gene environment interactions in the etiology of psychiatric disorders has gained momentum. We used multivariate GEE regression modeling to investigate the interaction between genes of the DISC1 pathway and birth weight, in relation to...
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