Article
Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.
Biological psychiatry - 15 Jun 2009
Tomppo Liisa, Hennah William, Lahermo Päivi, Loukola Anu, Tuulio-Henriksson Annamari, Suvisaari Jaana, Partonen Timo, Ekelund Jesper, Lönnqvist Jouko, Peltonen Leena
Abstract excerpt
BACKGROUND: Disrupted in Schizophrenia 1 (DISC1) is currently one of the most interesting candidate genes for major mental illness, having been demonstrated to associate with schizophrenia, bipolar disorder, major depression, autism, and Asperger's syndrome. We have previously reported a DISC1 haplotype, HEP3, and an NDE1 spanning tag haplotype to associate to schizophrenia in Finnish schizophrenia families....
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