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Common genetic variants with fetal effects on birth weight are enriched for proximity to genes implicated in rare developmental disorders.

Human molecular genetics - 31 May 2021

Beaumont Robin N, Mayne Isabelle K, Freathy Rachel M, Wright Caroline F

Abstract excerpt

Birth weight is an important factor in newborn survival; both low and high birth weights are associated with adverse later-life health outcomes. Genome-wide association studies (GWAS) have identified 190 loci associated with maternal or fetal effects on birth weight. Knowledge of the underlying causal genes is crucial to understand how these loci influence birth weight and the links between infant and adult...

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Identifiers

PMID: 33682876
DOI: 10.1093/hmg/ddab060
PMCID: PMC8355446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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