Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression profile of normal and cancer-associated fibroblasts according to intratumoral inflammatory cells phenotype from breast cancer tissue.

Molecular carcinogenesis - 1 Nov 2016

González Lucía, Eiro Noemi, Fernandez-Garcia Belen, González Luis O, Dominguez Francisco, Vizoso Francisco J

Abstract excerpt

The biological heterogeneity of breast cancer leads to the need for finding new approaches to understand the mechanisms implicated in breast cancer progression. The tumor stroma appears as a key in the progression of solid tumors towards a malignant phenotype. Cancer associated fibroblasts (CAFs) may orchestrate a functional "corrupted" stroma which in turn helps metastatic spread. In this study, we investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-Associated Fibroblasts
Share to Coculture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Fibroblasts

Share to Gene Expression Regulation, Neoplastic

Share to MCF-7 Cells

Share to Transforming Growth Factor beta

Share to Tumor Microenvironment

Source

Identifiers

PMID: 26349857
DOI: 10.1002/mc.22403

Genes

MMP11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression profile of normal and cancer-associated fibroblasts according to intratumoral inflammatory cells phenotype from breast cancer tissue.PMID 26349857Read ↗

Integrating spatial and single-cell transcriptomes reveals the role of COL1A2(+) MMP1(+/-) cancer-associated fibroblasts in ER-positive breast cancerSemantic proximity Read ↗

Role of cancer-associated fibroblasts in breast cancer development and prognosisSemantic proximity Read ↗

Cancer-associated fibroblasts induce an aggressive phenotypic shift in non-malignant breast epithelial cells via interleukin-8 and S100A8.Semantic proximity Read ↗

Cancer-Associated Fibroblasts in the Breast Tumor MicroenvironmentSemantic proximity Read ↗

Biological Characteristics and Genetic Heterogeneity between Carcinoma-Associated Fibroblasts and Their Paired Normal Fibroblasts in Human Breast CancerSemantic proximity Read ↗

MMP1 and MMP11 expression in Peripheral Blood Mononuclear Cells upon their interaction with Breast Cancer Cells and FibroblastsSemantic proximity Read ↗

Diversity and Biology of Cancer-Associated FibroblastsSemantic proximity Read ↗

Role of oxidative stress and the microenvironment in breast cancer development and progression.Semantic proximity Read ↗

Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast.Semantic proximity Read ↗

Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF-α and the NF-κB pathwaySemantic proximity Read ↗

Breast Cancer CAFs: Spectrum of Phenotypes and Promising Targeting Avenues.Semantic proximity Read ↗

Cancer-associated fibroblasts rewire the estrogen receptor response in luminal breast cancer, enabling estrogen independenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.