Article
Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast.
Oncogene - 25 Mar 2010
Bauer M, Su G, Casper C, He R, Rehrauer W, Friedl A
Abstract excerpt
Breast carcinoma invasion is associated with prominent alterations in stromal fibroblasts. Carcinoma-associated fibroblasts (CAF) support and promote tumorigenesis, whereas normal mammary fibroblasts (NF) are thought to suppress tumor progression. Little is known about the difference in gene expression between CAF and NF or the patient-to-patient variability in gene expression. Paired CAF and NF were isolated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.