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Article

Cancer-associated fibroblasts induce an aggressive phenotypic shift in non-malignant breast epithelial cells via interleukin-8 and S100A8.

Journal of cellular physiology - 1 Oct 2021

Lim Hyesol, Koh Minsoo, Jin Hao, Bae Mijeong, Lee Seung-Yeon, Kim Kyoung Mee, Jung Joohee, Kim Hyun Jeong, Park So Yeon, Kim Hoe Suk, Moon Woo Kyung, Hwang Sejin, Cho Nam Hoon, Moon Aree

Abstract excerpt

Cancer-associated fibroblasts (CAFs) in the tumor microenvironment have been associated with tumor progression in breast cancer. Although crosstalk between breast cancer cells and CAFs has been studied, the effect of CAFs on non-neoplastic breast epithelial cells is not fully understood to date. Here, we investigated the effect of CAFs on aggressive phenotypes in non-neoplastic MCF10A breast epithelial cells....

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Identifiers

PMID: 33748944
DOI: 10.1002/jcp.30364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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