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Article

Single nucleotide polymorphism genotyping using locked nucleic acid (LNA).

Expert review of molecular diagnostics - 1 Jan 2003

Mouritzen Peter, Nielsen Alex Toftgaard, Pfundheller Henrik M, Choleva Yoanna, Kongsbak Lars, Møller Søren

Abstract excerpt

Locked nucleic acid (LNA) is a new class of bicyclic high affinity DNA analogs. LNA-containing oligonucleotides confer significantly increased affinity against their complementary DNA targets, increased mismatch discrimination (delta Tm) and allow full control of the melting point of the hybridiz...

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Identifiers

PMID: 12528362
DOI: 10.1586/14737159.3.1.27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12528362-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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