Article
Increased frequency of circulating Tc22/Th22 cells and polyfunctional CD38(-) T cells in HIV-exposed uninfected subjects.
Scientific reports - 8 Sept 2015
Oliveira Luanda M S, Lima Josenilson F, Cervantes Cesar A C, Casseb Jorge S, Mendonça Marcelo, Duarte Alberto J S, Sato Maria N
Abstract excerpt
Some individuals are resistant to HIV-1 infection despite repeated exposure to the virus, suggesting the presence of a complex antiviral response. Innate factors like IL-22 exert gut mucosal protection and polyfunctional T cells have been associated with low progression in HIV infection; therefore, we evaluated the frequencies of CD4+ and CD8+ T cell-secreting cytokines, including Tc22/Th22 cells and...
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