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Article

TB/HIV pleurisy reduces Th17 lymphocyte proportion independent of the cytokine microenvironment.

Tuberculosis (Edinburgh, Scotland) - 1 Jul 2016

Korb Vanessa C, Phulukdaree Alisa, Lalloo Umesh G, Chuturgoon Anil A, Moodley Devapregasan

Abstract excerpt

T-helper (Th) 17 cells are a pro-inflammatory subset of CD4(+) effector T-cells critical in mucosal immunity. Imbalances in Th17 cell proportion have been implicated in the pathogenesis of several diseases; however, this has not been adequately explored in tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection. Since Th17 cells are predominantly mucosally associated, we assessed Th17 proportion and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27450010
DOI: 10.1016/j.tube.2016.05.001

Genes

RORC
STAT3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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