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Article

HIV controllers with HLA-DRB113 and HLA-DQB106 alleles have strong, polyfunctional mucosal CD4+ T-cell responses.

Journal of virology - 1 Nov 2010

Ferre April L, Hunt Peter W, McConnell Delandy H, Morris Megan M, Garcia Juan C, Pollard Richard B, Yee Hal F, Martin Jeffrey N, Deeks Steven G, Shacklett Barbara L

Abstract excerpt

A small percentage of human immunodeficiency virus (HIV)-infected individuals, termed elite controllers, are able to spontaneously control HIV replication in blood. As the gastrointestinal mucosa is an important site of HIV transmission and replication as well as CD4+ T-cell depletion, it is important to understand the nature of the immune responses occurring in this compartment. Although the role of the...

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Identifiers

PMID: 20719952
DOI: 10.1128/JVI.00980-10
PMCID: PMC2953185

Genes

MIP
TNF

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