Article
Highly specific detection of genetic modification events using an enzyme-linked probe hybridization chip.
Genetics and molecular research : GMR - 10 Aug 2015
Zhang M Z, Zhang X F, Chen X M, Chen X, Wu S, Xu L L
Abstract excerpt
The enzyme-linked probe hybridization chip utilizes a method based on ligase-hybridizing probe chip technology, with the principle of using thio-primers for protection against enzyme digestion, and using lambda DNA exonuclease to cut multiple PCR products obtained from the sample being tested into single-strand chains for hybridization. The 5'-end amino-labeled probe was fixed onto the aldehyde chip, and...
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