Article
DNA chips: a new tool for genetic analysis and diagnostics.
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine - 1 Jun 2001
Cuzin M
Abstract excerpt
DNA chips are miniaturized microsystems based on the ability of DNA to spontaneously find and bind its complementary sequence in a highly specific and reversible manner, known as hybridization. Labeled DNA molecules in a sample are analyzed by DNA probes tethered at distinct sites on a solid support. The composition of the DNA sample is then deduced by analyzing the signal generated by labels present at each...
Topics
- DNA Probes
- DNA, Neoplasm
- Equipment Design
- Gene Expression Profiling
- Genes, ras
- Genotype
- Gold
- Humans
- Microelectrodes
- Neoplasms
- Oligonucleotide Array Sequence Analysis