Resequencing and mutational analysis using oligonucleotide microarrays.

doi:10.1038/4469

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Article

Resequencing and mutational analysis using oligonucleotide microarrays.

Nature genetics - 1 Jan 1999

Hacia J G

Abstract excerpt

Oligonucleotide microarray (DNA chip)-based hybridization analysis is a promising new technology which potentially allows rapid and cost-effective screens for all possible mutations and sequence variations in genomic DNA. Here, I review current strategies and uses for DNA chip-based resequencing...

Topics

Animals
DNA Mutational Analysis
Genetic Variation
Genome
Humans
Oligonucleotide Array Sequence Analysis
Oligonucleotide Probes
Sensitivity and Specificity

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