Article
Resequencing and mutational analysis using oligonucleotide microarrays.
Nature genetics - 1 Jan 1999
Hacia J G
Abstract excerpt
Oligonucleotide microarray (DNA chip)-based hybridization analysis is a promising new technology which potentially allows rapid and cost-effective screens for all possible mutations and sequence variations in genomic DNA. Here, I review current strategies and uses for DNA chip-based resequencing and mutational analysis, the underlying principles of experimental designs, and future efforts to improve the...
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