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Article

Re-Sequencing of the APOL1-APOL4 and MYH9 Gene Regions in African Americans Does Not Identify Additional Risks for CKD Progression.

American journal of nephrology - 1 Jan 2015

Hawkins Gregory A, Friedman David J, Lu Lingyi, McWilliams David R, Chou Jeff W, Sajuthi Satria, Divers Jasmin, Parekh Rulan S, Li Man, Genovese Giulio, Pollack Martin R, Hicks Pamela J, Bowden Donald W, Ma Lijun, Freedman Barry I, Langefeld Carl D

Abstract excerpt

BACKGROUND: In African Americans (AAs), APOL1 G1 and G2 nephropathy risk variants are associated with non-diabetic end-stage kidney disease (ESKD) in an autosomal recessive pattern. Additional risk and protective genetic variants may be present near the APOL1 loci, since earlier age ESKD is observed in some AAs with one APOL1 renal-risk variant, and because the adjacent gene MYH9 is associated with nephropathy in...

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Share to Apolipoprotein L1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulosclerosis, Focal Segmental

Share to Hypertension, Renal

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Source

Open in PubMed Open full text

Identifiers

PMID: 26343748
DOI: 10.1159/000439448
PMCID: PMC4589514

Genes

APOL1
MYH9
APOL4
APOL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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