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Article

Circadian Modulation of 8-Oxoguanine DNA Damage Repair

4 Sept 2015

Abstract excerpt

The DNA base excision repair pathway is the main system involved in the removal of oxidative damage to DNA such as 8-Oxoguanine (8-oxoG) primarily via the 8-Oxoguanine DNA glycosylase (OGG1). Our goal was to investigate whether the repair of 8-oxoG DNA damage follow a circadian rhythm. In a group of 15 healthy volunteers, we found a daily variation of Ogg1 expression and activity with higher levels in the morning...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26337123
DOI: 10.1038/srep13752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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