Article
Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans
27 Feb 2021
Abstract excerpt
Circadian disruption has been identified as a risk factor for health disorders such as obesity, cardiovascular disease, and cancer. Although epidemiological studies suggest an increased risk of various cancers associated with circadian misalignment due to night shift work, the underlying mechanisms have yet to be elucidated. We sought to investigate the potential mechanistic role that circadian disruption of...
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