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Article

MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration.

Ophthalmology - 1 Nov 2015

Akagi-Kurashige Yumiko, Yamashiro Kenji, Gotoh Norimoto, Miyake Masahiro, Morooka Satoshi, Yoshikawa Munemitsu, Nakata Isao, Kumagai Kyoko, Tsujikawa Akitaka, Yamada Ryo, Matsuda Fumihiko, Saito Masaaki, Iida Tomohiro, Sugahara Masako, Kurimoto Yasuo, Cheng Ching-Yu, Khor Chiea-Chuen, Wong Tien-Yin, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD) is the leading cause of severe visual impairment. Despite treatment, a central scotoma often remains. The size of the scotoma depends on the lesion size of the choroidal neovascular membrane and significantly affects the patient's quality of life, a...

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Source

Identifiers

PMID: 26337002
DOI: 10.1016/j.ophtha.2015.07.032

Genes

MMP20
ARMS2
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26337002-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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