Article
Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration.
PloS one - 1 Jan 2015
Grassmann Felix, Fleckenstein Monika, Chew Emily Y, Strunz Tobias, Schmitz-Valckenberg Steffen, Göbel Arno P, Klein Michael L, Ratnapriya Rinki, Swaroop Anand, Holz Frank G, Weber Bernhard H F
Abstract excerpt
Worldwide, age-related macular degeneration (AMD) is a serious threat to vision loss in individuals over 50 years of age with a pooled prevalence of approximately 9%. For 2020, the number of people afflicted with this condition is estimated to reach 200 million. While AMD lesions presenting as geographic atrophy (GA) show high inter-individual variability, only little is known about prognostic factors. Here, we...
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