Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.

Cell and tissue research - 1 Mar 2016

Ishimura Akihiko, Terashima Minoru, Tange Shoichiro, Suzuki Takeshi

Abstract excerpt

Genetic studies have shown that aberrant activation of p53 signaling leads to embryonic lethality. Maintenance of a fine balance of the p53 protein level is critical for normal development. Previously, we have reported that Jmjd5, a member of the Jumonji C (JmjC) family, regulates embryonic cell proliferation through the control of Cdkn1a expression. Since Cdkn1a is the representative p53-regulated gene, we have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fibroblasts
Share to Embryo, Mammalian
Share to Embryonic Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Genetic Loci

Share to Jumonji Domain-Containing Histone Demethylases

Share to Tumor Suppressor Protein p53

Share to Up-Regulation

Source

Identifiers

PMID: 26334721
DOI: 10.1007/s00441-015-2276-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.PMID 26334721Read ↗

Down-regulation of JMJD5 suppresses metastasis and induces apoptosis in oral squamous cell carcinoma by regulating p53/NF-κB pathwaySemantic proximity Read ↗

Jumonji domain protein JMJD5 functions in both the plant and human circadian systems.Semantic proximity Read ↗

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila.Semantic proximity Read ↗

Mdm proteins: critical regulators of embryogenesis and homoeostasisSemantic proximity Read ↗

Roles of jumonji and jumonji family genes in chromatin regulation and development.Semantic proximity Read ↗

JMJD1C Ensures Mouse Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming through Controlling MicroRNA Expression.Semantic proximity Read ↗

p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5Semantic proximity Read ↗

Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.Semantic proximity Read ↗

JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by HydroxylationSemantic proximity Read ↗

The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila.Semantic proximity Read ↗

The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.Semantic proximity Read ↗

JMJD5 (Jumonji Domain-containing 5) Associates with Spindle Microtubules and Is Required for Proper Mitosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.