Article
Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.
Gene expression patterns : GEP - 1 Dec 2005
Machka C, Kersten M, Zobawa M, Harder A, Horsch M, Halder T, Lottspeich F, Hrabé de Angelis M, Beckers J
Abstract excerpt
The Notch signaling pathway has pleiotropic functions during mammalian embryogenesis. It is required for the patterning and differentiation of the presomitic and somitic paraxial mesoderm and of the neural tube. We used DNA-chip expression profiling and 2D-gel electrophoresis combined with peptide mass fingerprinting to identify genes and proteins differentially regulated in E10.5 Dll1 (delta-like 1, Delta1)...
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