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Article

Micropatterning transcriptionally and phenotypically reprograms endothelial cells.

Acta biomaterialia - 1 Apr 2026

Josic Dominovic Paula, Fallon Meghan E, Pang Jiaqing, Alese Theodora T, Le Hillary H, Anderson Deirdre E J, McCarty Owen J T, Barnes Anthony P, Hinds Monica T

Abstract excerpt

Vascular occlusions are a major cause of cardiovascular disease and require interventions including graft bypass surgery; yet, the development of synthetic vascular grafts remains a challenge due to the inability of synthetic biomaterials to support an anti-immunogenic endothelium. Topographical micropatterning of biophysical cues offers a promising strategy to enhance graft endothelialization. As the interface...

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Share to Endothelial Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41862111
DOI: 10.1016/j.actbio.2026.03.029
PMCID: PMC13082738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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